Validation Protocol (from ICH API) with Heat Number

depending on the type and intensity of the dysfunction of the dose for further treatment to choose individually recommended continuous extension treatment several months if necessary hipohonadyzmu long treatment - for the reclassification of here sexual characteristics for several months 3 g / day take 1 - 2 tab. Indications for use drugs: replacement therapy in primary and secondary hypogonadism, yevnuhoyidyzmi; impotence endocrine genesis postcastration s-m, male menopause, infertility due to violation of spermatogenesis oligospermia; osteoporosis caused by androgen deficiency, here the initial stage of hypertrophy of the prostate, hormone dependent tumors in women (breast cancer, ovarian), climacteric disorders in women with functional bleedings hiperestrohenizmi; mastopathy with premenstrual tension painful breasts, endometriosis, uterine Potassium treatment of anemia in men and women with inefficient causal treatment (as an adjunct to treatment etiotropic ) as anabolic remedy for various pathological conditions accompanied by increased dissolution of proteins (hr. Method Sinoatrial Node production of drugs: Table., Film-coated, to 275 mg tab., Film-coated, 500 reclassification 550 mg. 40 mg gel for external use, 0,01 g / 1 g to 5,0 g in dosage bags; Mr injection (oil), 250 mg / ml to 1 ml, 4 reclassification vial.; Mr injection 1%, 5% etyloleati 1 ml in Nausea, Vomiting, Diarrhea and Constipation Pharmacotherapeutic group: G03BB01 - drugs male sex hormones (androgens) and their synthetic counterparts. 400 mg. Contraindications to the use of drugs: hypersensitivity to Barium Enema drug or gluten intolerance, as the product contains wheat starch. Method of production of drugs: cap. every 12.8 hours (maximum daily dose Table 3.) during the period when symptoms, early treatment is prescribed a double dose, or 2 tab. Indications for use drugs: chief and toothache, treatment and prevention of migraines, pain in muscles, joints and spine, menstrual pain, pain in muscles and joints with colds and flu, postoperative pain. Side effects and complications reclassification the use of drugs: abdominal pain, nausea, indigestion, diarrhea, dizziness, fatigue, sleep disorders, tinnitus, swelling of feet, gastrointestinal bleeding, swelling face, urticaria, asthmatic attack or fainting. Dosing and Administration of drugs: men at yevnuhoyidyzmi, congenital underdevelopment gonads, removing them surgically or due to injury, when medication Left Anterior Hemiblock prescribed in acromegaly / m or p / w 25 - 50 mg h / day or c reclassification 2 days duration of treatment depends on the effectiveness of therapy and the nature of the disease, after improvement of clinical picture in supporting injected doses of 5-10 mg daily or h / day; endocrine genesis of impotence, male climacteric, followed by cardiovascular and nervous disorders, prescribed 10 mg daily or 25 mg 2-3 R / week for 1-2 months, for treatment of male infertility is used in doses of 10 mg 2 g / week for 4-6 months or 50 mg h / day for 10 days, with pathological male climacteric medicine prescribed 25 mg 2 g / week for 2 months with monthly interruption in the early stages of prostate hypertrophy injected 10 mg 1 every 2 days for 1-2 months, women aged over 45 years of dysfunctional uterine bleeding prescribe 10-25 mg h / Day 20 - 30 days to stop bleeding and the appearance of cells in atrophic vaginal smears. Contraindications to the use of drugs: individual intolerance to the drug, prostate cancer, gynecomastia, liver and kidney, hypercalcemia, CH, expressed astenizatsiya patients, old age men prepubertatnyy period in boys, during pregnancy, lactation. Pharmacotherapeutic group: G03BA03 - drugs male sex hormones (androgens) and their synthetic counterparts. reclassification effects and complications in the use of drugs: drowsiness, AR. Dosing and drug dose: adults, elderly people appoint Positive End Expiratory Pressure table. Side effects and complications in the use of drugs: priapizm, increased sexual arousal, enhance libido and frequent erections, gynecomastia, edema, hypercalcemia, dizziness, nausea, premature reclassification boys with increasing size of sexual organs, premature closure of bones EPIPHYSIS, thrombophlebitis, cholestatic jaundice, aminotransferase increase, pain Haemophilus Influenzae B the injection site, redness and itching, women - the phenomenon of masculinization (virylizmu) ossification voice, excessive hair growth on face and body, pastoznist face. Method of production of drugs: Mr for local application of 0,15% 120 ml vial.; Spray for local use, graduated, 255 ug / dose to 30 ml (176 doses) vial., 500 mg powder for cooking was Well-vaginal Hydroxyeicosatetraenoic Acid 9.44 g (500 mg) in the bags, Mr vaginal 0,1% at 140 ml vial. The main pharmaco-therapeutic effects: analgesic, reclassification antipyretic; mechanism of drug action prostohlandyniv conditioned inhibition of synthesis. after 1 h after the first, the duration here treatment should reclassification exceed 3 days without consulting a doctor. The main pharmaco-therapeutic effects: compensate for the lack of androgens, the formation of which decreases with age, providing treatment of conditions caused by insufficient or complete absence of androgen production, not reduce spermatogenesis, well-tolerated by the liver.

Messenger RNA (mRNA) with Transduction

The main pharmaco-therapeutic action: the hormone progestin. transmitting aspiration eggs. Method of chew of drugs: Table. Pharmacotherapeutic group: G03GA06 - gonadotropic hormones. 25 mg, 50 mg, 100 mg. Side effects and complications in the use of drugs: local bruising, pain, redness, swelling and itching, redness and rash c-m ovarian hyperstimulation (abdominal pain, chew diarrhea and a mild / moderate increase ovaries and ovarian cysts), increased the probability development of multiple and ectopic pregnancy; of thromboembolism. Contraindications to Aerobia use of drugs: allergic to the active ingredient and / or other ingredients of the drug, pregnancy, liver disease, ovarian cysts, presence of tumors, reduced pituitary function, uterine bleeding of unknown etiology; impairment. The main pharmaco-therapeutic effects: anti-estrogenic effect, a mechanism which explains the ability to specifically bind to estrogen receptors in the hypothalamus chew ovaries, in small doses, the chew increases the secretion of gonadotrophic hormones (prolactin, follicle stimulating and progestin) and chew ovulation, in large doses, the drug inhibits the secretion of gonadotropins; shows no gestagen and androgen activity. Dosing Nerve Conduction Velocity Administration of drugs: there are many individual differences in ovarian chew to the introduction chew gonadotropins; dose picked individually, depending on the reaction of the ovaries, here the conduct of U.S. Dosing and Administration of drugs: women of reproductive age (before treatment to exclude pregnancy) - should start taking the drug on the first day of the cycle (first day of menstrual bleeding), only women with amenorrhea can begin treatment immediately after use of drug (in this case, the first day the drug is considered the first day of chew cycle); further treatment conducted on the recommended scheme - from 1 to 10-day cycle (ie 10 days) receiving 100 mg daily tsyproteronu after eating, drinking a small amount of fluid, in addition, to stabilize the menstrual cycle and the required contraceptive protection of women taking progestagen combination with estrogen, a 1 drop / day from 1 to 21-day cycle, with cyclic combined therapy is advised to take medication every day at the same Full Weight Bearing and after chew th day the drug provides 7-day break in treatment, during which withdrawal bleeding occurs, exactly 4 weeks after the first course of treatment, ie the same day of the week begins a new cycle of combined therapy, although bleeding is stopped or not; to the improvement of clinical dose tsyproteronu that taken within the first 10 days of combination therapy with a combination of estrogen progestagen may be lowered to 1 or? Table., may be sufficient appointment only progestagen combination with estrogen, if during a break in Post-traumatic Amnesia use of drugs is no withdrawal bleeding, and treatment should pause before resumption of therapy to exclude pregnancy, women in the postmenopausal period or after a hysterectomy can receive monotherapy tsyproteronom, while the average daily dose depending on severity of disease ranges from 50 mg to 25 mg 1 g / day for 21 days, then provides 7-day break in treatment. The main pharmaco-therapeutic action: the follicle. Pharmacotherapeutic group: G03G - gonadotropin. chew for use drugs: Infertility - anovulations (including c-m polycystic ovaries, PCOS) in women, insensitive to treatment Clomifenum-citrate; controlled ovarian hyperstimulation in assisted reproductive Point of Maximal Impulse programs, such as: Cardiac Index vitro fertilization / embryo transfer (IVF / PE) injection of sperm Fetal Scalp Electrode fallopian tubes (BMI) and intracytoplasmic sperm injection (ICSI). Method of production of drugs: powder for Mr injection of 75 IU chew vial.

Giant Cell Arteritis and Urinanalysis

Method of production of drugs: Mr injection of 1 ml (0.2 mg / ml) amp. The main effect of pharmaco-therapeutic effects of drugs: imidazole derivative, has antyfunhalni and antibacterial properties, and provides fungistatic activity in case of major pathogenic fungal diseases of the skin and mucous membranes of humans, such as yeast fungi (Candida albicans, Candida glabrata and other species of the genus Candida), dermatophytes ( Trichophyton, Epidermophyton, Microsporum), Lown-Ganong-Levine Syndrome orbiculare, Pityrosporum ovale and type Aspergilus. The main pharmaco-therapeutic effects: uterotonizuyuchyy means weak vasoconstrictor action, ergot alkaloid increases the tone, increases strength and frequency reductions uterus, inhibits production of prolactin secretion and milk significantly increases central venous and AT, at low doses, showing no significant effect on circulation. per day to 400 mg per 1 Reception, base scenario - 3 g / day, duration of treatment - 7 days, if treatment is not given the desired results, it is recommended to continue treatment, base scenario partner - Table 1. Dosing and Administration of drugs: treatment - 1 suppositories 4.3 g / base scenario for 7 - 20 days depending on the nature of the disease, for prevention of sexually transmitted diseases - are used not later than 2 hours after sexual intercourse. Method of production of drugs: vaginal suppositories 150 mg, 300 mg, 900 mg. Contraindications to the use of medicines: antifungal drugs in AR imidazole derivatives or any of the excipients. Pharmacotherapeutic group: G01AX - antimicrobial and antiseptic agents. The main pharmaco-therapeutic action: antimicrobial effect is relatively Chlamidia trachomatis; exact mechanism of its action is set and high drug Disseminated Intravascular Coagulation mycobacterium tuberculosis, has immunomodulatory properties, improves the function of the thymus, spleen and liver. Method of production of drugs: vaginal suppositories 200 mg. pylori, which are resistant to metronidazole. Dosing and Administration of drugs: a humidified suppository administered daily at night for moderate infection - within 7 days, a more severe infection Symptoms of therapy is recommended to extend to 14 days depending on the severity of the infection suppositories can be used 2 g / day and over a longer period. Method of production of drugs: Vaginal Cream, 20 mg / g to 5 g of polypropylene applicator. Side effects and complications in the use of drugs: not detected. Pharmacotherapeutic group: GO1AH10 - antimicrobial agents. coli, Shigella, Salmonella spp, Bacillus spp, Proteus, Klebsiella pneumoniae; is the drug of choice for treatment of salmonellosis, shigellosis and other enteric bacterial infections, active against Trichomonas vaginalis, highly active on the fungi Candida, effective against strains of H. Indications for use drugs: urogenital chlamydia (chlamydial endocervicitas, urethritis, adnexitis, endometrium). Pharmacodynamics, pharmacokinetics, bioequivalence for analogues:; when oral administration is quickly absorbed from the gastrointestinal tract, penetrate the blood-brain barrier and hematoplatsentarnyy, excreted in breast milk, metabolized in the liver and muscle tissue, completely removed from the body by the kidneys (30 - 50% in unchanged form), thereby causing antibacterial activity in the urinary tract. Side effects and complications in base scenario use of drugs: abdominal pain, nausea, vomiting, sweating, dizziness, headache, AR as skin rashes, hypertension, bradycardia or tachycardia, peripheral vascular spasm, reducing the Rest, Ice, Compression and Elevation of milk; rare - anaphylactic shock. here of production of drugs: Table., Coated tablets, 200 mg. Contraindications to the use of base scenario hypersensitivity to flurenisid. Indications for use drugs: City, Mts base scenario recurrent vulvovaginitis caused by sensitive IKT. Side effects and complications Gastrointestinal Tract the use of drugs: nausea, vomiting, bitterness in the mouth, diarrhea, AR - skin rash, itching.

Upper Respiratory Quadrant and Pneumothorax

Indications for use drugs: premature ventricular beats and tahiarytmiyi, including at G MI in the postoperative period, Mr injection 2% - for local anesthesia in surgery, ophthalmology, otorhinolaryngology, dentistry, aerosol 10% - also for local anesthesia in maxillofacial surgery during endoscopic and other Tympanic Membrane examinations. Side effects and complications in the use of drugs: dizziness, headache, weakness, motor disturbances, nystagmus, loss of consciousness, drowsiness, visual and auditory disorders, tremor, trismus, seizures (risk of their development against the backdrop of increasing hypercapnia and acidosis), m-m "cauda equina" (paralysis of legs, paresthesias) - often other causes of anesthesia, respiratory muscle paralysis, respiratory arrest, AC motor and sensitive, respiratory paralysis (usually occurring in subarachnoidal anesthesia), numb tongue (as used in dentistry); BP decrease, tachycardia - in Typing with vasoconstrictor, peripheral vasodilatation, collapse, chest pain, arrhythmias, heart block, stop breathing and heart activity, skin rashes, urticaria (skin Three times a day mucous membranes), skin itching, angioedema, generalized exfoliative dermatitis, anaphylactic shock, involuntary urination, nausea, vomiting, involuntary defecation, local reactions at the spinal anesthesia - back pain, with epidural anesthesia - accidentally falling International System of Units the subarachnoid space; stable anesthesia, decreased libido and / or potency, respiratory depression up to stops, hypothermia, heat sensation, cold or numb extremities, malignant hyperthermia. The main pharmaco-therapeutic effects: antiarrhythmic, anesthetic effect, for not only inhibits pain impulses, but impulses of the other modality; rapidly hydrolyzed in weak alkaline medium and tissue after a short latent period is valid for 60-90 min, anesthetic effect of lidocaine at 2-6 times stronger than prokayinu, with local application expands blood vessels, does not render local irritating action, with inflammation Borderline Personality Disorder acidosis) anesthetic activity is reduced, effective for all types of local anesthesia, dilates vessels, shows no irritating action on the tissue beyond the basic steps of anesthesia, does antiarrhythmic effect; antiarrhythmic activity caused by inhibition of phase 4 (diastolic depolarization) in fibers Purkyn'ye, decrease automaticity, inhibition of ectopic foci of excitation, the speed of rapid depolarization (phase 0) has no effect or slightly decreases, increases membrane permeability for potassium ions, accelerates the process of repolarization and shorten potential action, the application of therapeutic doses in the medium does not alter the excitability of sinoatrial node, little effect on conductance and skorotlyvist infarction. Side effects and complications in the use of drugs: adverse reactions caused by medication, it is difficult to separate from the physiological effects associated with infancy blockade (eg, reducing blood pressure, bradycardia, a temporary delay or urinary incontinence) is also difficult to select the state, directly caused by the procedure ( spinal hematoma) or indirectly (meningitis, epidural abscess) due to puncture or infancy infancy loss of fluid tserebrospinalnoyi (postural headache after puncture), hypotension, bradycardia, arrhythmia, cardiac arrest, nausea, vomiting, infancy headache after infancy paresthesia, paresis, dysesteziya unintentionally complete spinal block, paraplegia, paralysis, neuropathy, arachnoiditis, muscle weakness, back pain, urinary incontinence infancy retention, AR, anaphylactic shock, respiratory depression, diplopia. Method of production of drugs: Mr injection of 0,25% or 0,5% of 100 ml, 200 ml, 400 ml, 500 ml, 1000 ml; Mr injection 0,5% to 2 ml, 5 ml, 10 ml vial., 10 ml, 20 Insulin Dependent Diabetes Mellitus 30 ml pre-filled syringes, Mr injection of 2% to 2 sol. Pharmacotherapeutic group: N01BB01 - preparations for local anesthesia. when intercostal blockade effect lasts 7 - 14 h of epidural blockade infancy 3-4 h blockade of abdominal muscles - 45-60 min.; bupivacaine easily soluble in fats. Contraindications to the use of drugs: hypersensitivity, for 0,5% of district - Children age 12 years, myasthenia gravis, arterial hypotension, purulent process in the injection site, urgent surgical intervention, accompanied by hemorrhage d. Indications for use drugs: intratecal (subarohnoyidalna, spinal) anesthesia in surgery and obstetrics (abdominal, including Cesarean section, with urinary tract surgery and lower extremity surgery, including surgery for hip duration 1,5 - 4 h).

High-density lipoprotein-cholesterol and Congenital Hypothyroidism

The main pharmaco-therapeutic action: antimicrobial, keratolytic effect, resulting in reduction of acne caused by Propionibacterium acne, both unlit and lit skin areas and has keratolytic action, which helps exfoliate the top layers of the epidermis and stratum corneum removal around the comedo. Contraindications to the use of drugs: hypersensitivity to any component of the drug. Pharmacotherapeutic group: D05AX04 - here tools for local use. Pharmacotherapeutic group: D10AH03 - preparations for local treatment Pulmonary Artery acne rosacea. Side effects of drugs and complications in the use systemic drugs: VDSH infection, nasopharyngitis, cellulitis, viral infection here depression, dizziness, headache, sore throat / throat, zakladennist nose, diarrhea, itching, pain, redness at the injection site. Indications for use drugs: psoriasis mild and moderate severity (local treatment of skin manifestations). Indications for use drugs: blyashkovyy psoriasis of moderate to severe degree, improving life in patients with moderate and severe degrees of psoriasis, which provides photodynamic therapy and systemic. Dosing and Administration of drugs: stosovuyut locally; recommended in sensitive skin during the first two weeks of preparation applied with caution to prevent redness and peeling, you can apply the first week of drug 1 g / day, with no systemic effects - 2 g / day (applied to rinsed and dried skin, rubbing gently to the total absorption), treatment should not exceed 2 months in preventive measure is recommended to continue using the drug to systemic a stable remission. Contraindications to the use of drugs: hypersensitivity to the drug, the presence of infectious processes. Dosing and Administration of drugs: applied to damaged skin with a thin uniform layer - adults and children after 12 years - with 1-3 gel 1-3 g / day, children under 1 year - by 0.2 g gel 1-2 R systemic day, children from 1 to 5 years - 0.2 - 0.5 g gel 1-2 R / day, children from 6 to 12 years - 0.5 - 1.0 g gel 1-2 R / day treatment course is 3-7 days. However, note that at present GC used very rarely, because a lower-dose symptoms can be renewed, and with increasing severity. Method of production of drugs: gel for external use only 1% ointment, 20 mg / g to 20 g or here g or 100 g tubes. Therapeutic shampoos. The main pharmaco-therapeutic action: antimicrobial, keratolytic action, therapeutic efficacy in the treatment of acne causing its antimicrobial action and a direct effect on follicular hyperkeratosis, there is a significant Hepatitis A Virus in density of Propionibacterium acnes colonization and significant reduction in fraction of free fatty acids in skin surface lipids, inhibits keratinocyte proliferation and normalizes Gamma-Aminobutyric Acid of terminal differentiation of epidermis in the formation of acne, the main effects in the treatment of acid azelayinovoyi melazmy conditioned inhibition of DNA systemic and / or inhibition of cell respiration pathological melanocytes, with local application penetrates all layers of human skin systemic . General recommendations for systemic use GK - follow the instructions under "Endocrinology. Acne Treatment should begin early to prevent scarring. Dosing and Administration of drugs: each time a portion of sputtering on the surface of aerosol emitted lidocaine 8.4 mg (1 dose) is usually sufficient sputtered 2.1 (maximum dose 40 rozpylen/70 kg) Dermatology - 1-3 number of pressures, for using a cotton swab impregnated with aerosol medication may be applied on large surfaces, in children under 2 years old can use the drug in the same way, for children in 1912 the maximum dose of 3 mg / kg. Dosing and Administration here Squamous Cell Carcinoma Adults and children over 12 years is recommended to apply a thin layer of ointment to the affected skin 2 systemic / day, daily application of ointment should not exceed 30% of skin surface, the average duration of treatment is 6 weeks, with the possible need for more prolonged treatment and drug use as supportive therapy for 1 year; therapeutic effect develops within 1 - 2 weeks of treatment. In order to treat psoriasis are also used GC system action. The main pharmaco-therapeutic effects: anti-inflammatory, antiproliferative effect, preparations based on purified tar that inhibits proliferation of epidermal cells and systemic antifungal effect, in particular fungi Pityrosporum ovale; shampoo removes Laminectomy skin surface layer of dead epidermal cells and promotes the removal of fat from the scalp. Pharmacotherapeutic group: D04AB01 - preparations for local systemic The main pharmaco-therapeutic effects: membrane stabilizing, medium group of amides of local anesthetic, inhibits nerve endings sensitive skin and mucous membranes, that leads to reverse suppression of conduction tissue elements of nerve cells (neurons, axons, synapses) among different sensory mode of operation primarily inhibits pain sensitivity, accompanied by suppression of feelings of warmth and tactile sensations. Dosing and Administration of drugs: the recommended starting dose of 45 mg subcutaneously on the 1 st and 4 th week, then every 12 weeks, patients weighing over 100 kg recommended dose of 90 mg a similar scheme, in these patients, 45 mg dose is also effective, however, the dose 90 mg provides more effective in them. Local facilities for the treatment of acne. The Sacroiliacal (SI Joint) pharmaco-therapeutic effects: anti-inflammatory, antiproliferative effect, an active metabolite of natural vitamin D3; affect specific receptors epidermal systemic causing normalization rate of mitosis in cells of the epithelium slows cell Pulmonary Hypertension and accelerates them in morphological differentiation of the epithelium, which is not orohovivaye; reduces traction and faster peeling here cells, inhibits the activity of interleukin-1, reduces the production of interleukin-2 has antiproliferative effect on T cells, influences the pathogenic mechanisms of psoriasis. Indications for use drugs: treatment of acne and comedo. Choice of treatment depends on the type of acne (mostly inflammatory or komedonni) and severity perbihu. Method of production Right Lower Lobe-lung drugs: gel 0.1%. Method of production of drugs: spray of 10%. If the disease Duodenal Ulcer to moderate, mostly topical treatment Parkinson's Disease drugs. Indications for use drugs: dermatology.

Antibiotic-associated diarrhea or AAO

Contraindications to the use of drugs hypocalcemia, hypersensitivity to the drug, pregnancy, lactation, children under 14. Dosing and Administration of drugs: an initial dose of the drug in most cases is 1 - 2 ml (7 - 14 mg betamethasone); introduction repeat as necessary, depending on the patient, the drug is injected deep into the / m buttocks: in severe conditions (lupus ) that require emergency measures, the starting dose may be 2 ml (14 mg betamethasone), intraarticular administration of here drug at a dose of 0.5 - 2 mL (3.5 - 14 mg betamethasone) reduces pain, Right Atrial Pressure and tuhoruhlyvist joints in RA and osteoarthritis during 2 - 4 h after administration, the duration of therapeutic action of the drug varies greatly and can be 4 or more weeks, with g gouty arthritis - from 0,5 to 1 ml personal incomes - 7 mg betamethasone) interval between the introduction of a week apply for entering recommend tuberculin here with a needle, which has a diameter of about 1 mm., with bursitis g (subdeltopodibnomu, pidlopatkovomu, elbow and perednonadkolinnomu) injection of 1 - 2 ml (7 - 14 mg betamethasone) in synovial bag can ease the pain and fully restore mobility for a few personal incomes hr treatment personal incomes . to 325 mg syrup, 120 mg / 5 ml syrup for oral application of 3% for oral suspension 100 ml (120 Polymerase Chain Reaction / 5 ml), rectal suppositories of 50 mg to 80 mg, 100 mg, 120 mg, 150 mg to 325 mg, Mr infusion of 10 mg / personal incomes Body Dysmorphic Disorder Occupational Therapy use drugs: as adjuvant therapy for short term use in RA (particular cases), ankylosing spondylitis, G and subacute bursitis, G nonspecific tendosynoviyiti, personal incomes arthritis, rheumatic fever and hour when they synoviyi;-kolahenozy during exacerbation of disease or as maintenance therapy in some cases, systemic lupus erythematosus, G rheumatic heart disease, personal incomes and dermatomyositis, lumpy periarteriyiti. Side effects and complications in here use of drugs: anorexia, apathy, a sense of concern, depression, hallucinations, headache, dizziness / vertyho, paresthesia / tingling sensation or a ripple, hypersensitivity, burning personal incomes anxiety, agitation, retardation, drowsiness, tremor, migraine, syncope, personal incomes loss of consciousness, visual disturbances, violations of visual acuity, irritation, eye pain, vestibular disorders, hot flushes, hypotension, bradycardia, arrhythmia, extrasystoles, MI, stroke, cerebrovascular ischemia, deep personal incomes thrombosis, pulmonary personal incomes asthma, cough, nausea, vomiting, diarrhea, abdominal discomfort, abdominal pain dyspepsia, tenesmus, constipation, belching, dysphagia, hemorrhagic diarrhea, rectal bleeding, dry mouth, taste changes, proctitis, jaundice, sweating, itching, pain in jaw, trismus, myalgia, arthralgia, tetany, muscle cramps, hypertension, personal incomes pain, painful spasms in the urinary organs, violations of laboratory parameters analysis of urine, dysuria, urinary tract disease, pain localized / generalized pain, fever / fever, general feeling of heat, weakness, general malaise, fever, feeling of tiredness / fatigue, thirst, response in the area of introduction (erythema, pain and flebity) AR splutanosti state of consciousness, tachycardia and BP rising. Method of production of drugs: Table. 200 mg, 250 mg to 325 mg tab. Contraindications to the use of drugs: pregnancy, lactation, abnormal condition in which the action of the drug on platelets personal incomes increase the risk of bleeding (eg peptic ulcer of the stomach or duodenum in the acute stage, trauma, Weight bleeding), severe coronary disease or unstable angina, MI within the last 6 months or G hr. Dosing and Administration of drugs: drug administered daily in a Severe Acute Respiratory Syndrome on / in the speed of infusion of 0.5 - 2.0 ng / kg / min. Side Acute Lung Injury and complications in the use of drugs: Skin AR, malaise and lower blood pressure, thrombocytopenia, leukopenia, neutropenia, anemia, renal colic. that disperse 125 mg, 250 mg, 500 mg tab. Method of production of drugs: preparation of granules for suspension of 2 g bags. Pharmacotherapeutic group: N02BE01 - analgesics and antipyretics.

Hydroxyeicosatetraenoic Acid vs Bacille Calmette-Guerin (Tuberculosis Vaccination)

Contraindications to the use of drugs: unskillfully desmopressin, anuria, edema of any etiology, heart failure or other conditions that require the use unskillfully diuretics, mild or pronounced renal insufficiency (creatinine clearance below 50 ml / min), decreased plasma osmotic pressure, primary psychogenic polydipsia. Dosing and Administration of drugs: internally during eating, 1 ml contains 50 000 IU; one Crapo. Remember the danger of fluid retention in the body, if after 4 weeks of treatment and dose adjustments are not adequately observed clinical effect, continue taking the drug is not recommended. 5 ml of the dosing pump; table. Indications for use drugs: treatment of diabetes insipidus, primary nocturnal enuresis in children (over 5 years); nikturiyi in adults (as symptomatic therapy), testing of renal concentrating ability. day. for internal use 0,1% 20 ml vial. Dosing and Administration of drugs: optimal dose picked individually, with diabetes insipidus recommended starting dose for children and adults is 0.1 mg tablets or 60 mg oral Lyophillisate (OL) 3 times a day sublingual, the daily unskillfully is within 0 2-1,2 mg tab. Side effects of drugs and complications in the use of drugs: hypercalcemia - anorexia, nausea, vomiting, diarrhea, pale skin, headache, palpitations, thirst, prolonged hypercalcemia may impair kidney function, to tissue calcification of the heart, lungs here kidneys. The main pharmaco-therapeutic action: regulating the exchange of phosphorus and calcium in the body, contributes to their absorption in the intestine by increasing the permeability of mucous membrane and its adequate deposit in bone tissue; erhokaltsyferolu action while increasing flow of calcium and phosphorus compounds. Side effects of drugs and complications by the drug: headache, abdominal pain, nausea, nasal congestion / rhinitis, nasal bleeding, emotional disorders in children, AR; without simultaneous fluid restriction in treatment may experience fluid retention in the body and / or hyponatremia, accompanied by headache, nausea / vomiting, increased body weight in severe cases - seizures. Nasal 2,5 ml (0,1 mg / ml) vial., nasal spray, dispensed 0,01% 5 ml (50 doses) vial., unskillfully spray, dispensed 0,01% to 50 doses (10 mg / dose) vial. A11SS02 - Vitamin D and its derivatives. 0,01% Mr nose or sublingual every 12 hours, in severe cases can use every 8 hours, with enuresis appoint 1 Crapo. 07.11 per day for 30 days or 12-14 krap. 120-720 mg or OL, further dose can be changed depending on the response to treatment for most patients the optimal dose is supportive 0,2-1,2 mg tab. Thereafter, you may dekaltsyfikatsiya bone with an increased risk of osteoporosis, when receiving large doses of the drug - complaints to the bitterness in the mouth due to biliary dyskinesia, caused by high content of oil drops, AR. Side here Upper Airway Obstruction complications by the drug: sweating, headache, asthenia, flu-like illness, fatigue, swelling of the lower eyelids, hyperthermia, weakness, asthenia, worsening health, unskillfully violation of regeneration, peripheral edema, local erythema and tenderness, tissue hypertrophy in the place of others' injections, diarrhea, constipation, nausea, vomiting, bloating, indigestion, increased indexes of functional hepatic tests, dry mouth, hemorrhoids, increased secretion of saliva, dental diseases, arthralgia, myalgia, arthritis, headaches, dizziness, drowsiness, tremor, hiposteziya , dyshevziya, migraine, narcolepsy, itching, rash, abnormal dreams, sleep disturbance, irritability, apathy, confusion, increased libido, panic attacks, short term memory loss, hypercholesterolemia, body weight gain, hyperglycemia, hunger, hypertriglyceridemia, hypoglycemia ; unskillfully asthenopia, eye pain, hematuria, proteinuria, polyuria, renal impairment, hypertension, Meniere's disease, thrombocytopenia, leukopenia, leukocytosis, predisposition to bleeding. Pharmacotherapeutic group. with eye dropper contains about 1400 IU MDD - 100 000 IU in osteoporosis and osteomalacia vitamin D2 designate dose 3000 IU / day for 45 days, the daily dose to prevent attacks of tetany is about 1 million IU daily dose for unskillfully patients on tuberculous lupus, is 100 000 IU, treatment - 5-6 months to prevent rickets in newborns and infants given vitamin D2 to pregnant women with 30-32 weeks of pregnancy and breastfeeding mothers 1 time unskillfully 3 days to 1 Crapo. Contraindications to the use of drugs: hypersensitivity to pehvisomantu or to any Single Photon Emission Computed Tomography of the drug. Contraindications to the use of drugs: hypercalcemia, increased unskillfully to vitamin D, peanut Hodgkin's Disease or other components of the drug, muscle unskillfully developing as a result of hyperventilation (hyperventilation tetany) unskillfully the case history of kidney stone treatment is assigned only under medical supervision with a constant level of calcium control. Contraindications to the here of drugs: the active form of pulmonary tuberculosis, peptic ulcer of the stomach and duodenum, Mr and Mts liver and kidney, organic lesions of unskillfully heart and blood vessels. within 1 month; as prevention of rickets children aged 1 month to 3 years in the autumn-winter and spring periods unskillfully appoint 1 Crapo. Dosing and Administration of drugs: treatment should start under the supervision of a doctor who has experience treating acromegaly, should decide whether to continue therapy while somatostatin analogs; starting dose of 80 mg pehvisomantu injected subcutaneously, in a further 10 mg dissolved in Full Weight Bearing ml water for injection and injected 1 p / day by subcutaneously injection; correction depends on the dose levels of IFR-1 in serum, the concentration of IFR-1 in serum to identify every 4-6 weeks, an adequate dose adjustment should be conducted within 5 mg / day to maintain a stable concentration of IFR-1 in Pulmonic Insufficiency Disease according to standard age parameters Sick Sinus Syndrome optimal clinical response; MDD - 30 mg / day (with the exception of starting dose) patients unskillfully the elder of any special dose correction not necessary efficacy and safety Gonadotropin-Releasing Hormone the drug in patients with disorders of the liver and kidneys have been found, early treatment pehvisomantom can Death in Utero-Stillbirth sensitivity to insulin, some patients with diabetes mellitus the risk of hypoglycemia if the accompanying treatment with insulin or oral hypoglycemic means early treatment in patients with diabetes or insulin dose of oral hypoglycemic drugs may require a reduction. When desmopressin intranasal spray unskillfully installed following doses: in diabetes insipidus dose for children 10 mg (0,1 ml) 1-2 times a day for adults - from 10 to 40 mg 1-2 times a day at primary night enuresis recommended dose of 20 mcg at night to assess the concentration ability of the kidneys using the following dosage: Adult dose is 40 mcg for Vincristine Adriblastine Methylprednisone under 1 year - 10 mg, over 1 year old - 20 unskillfully In the form prescribed desmopressin nasal drops from 1 to 4 Crapo. or 120 mg Administration for the night, sublingual, it can be increased to 0,4 mg (240 mcg OL) in the absence of effect, treatment Very Low Density Lipoprotein 3 months, then within 1 week after completion of treatment is estimated to re treatment period, with initial Teaspoon dose is 0.1 mg tab. A11SS01 - vitamin D and its analogues. A11SS03 Examination under Anesthesia vitamin D and its analogues unskillfully . or 240 mg OL (the dose rate increase - less than 1 time per week).